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Database - Alliance francophone pour l'accouchement respecté (AFAR)

Description of this bibliographical database (AFAR website)
Currently 3046 records
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https://afar.info/id=1264

Created on : 24 May 2005
Modified on : 02 Dec 2007

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Bibliographical entry (without author) :

Birth outcomes after prenatal exposure to antidepressant medication. Am J Obstet Gynecol. 2003 Mar;188(3):812-5.

Author(s) :

Hendrick V, Smith LM, Suri R, Hwang S, Haynes D, Altshuler L.

Year of publication :

2003

URL(s) :

http://L’utilisation d’anti-dépresseurs pendant…

Résumé (français)  :

Abstract (English)  :

OBJECTIVE: The purpose of this study was to examine prospectively the incidence of congenital anomalies and neonatal complications after prenatal exposure to antidepressant medication.

STUDY DESIGN: Birth outcomes were obtained from a review of obstetric and neonatal records of 138 women who were treated with selective serotonin reuptake inhibitor antidepressant medications (SSRIs) during pregnancy.

RESULTS: The incidence of congenital anomalies in this study was 1.4%, comparable to general population rates. Rates of low birth weight and preterm births were low, occurring in 2.9% and 6.5% of births, respectively. The low birth weight infants had been exposed to relatively high doses of fluoxetine (40-80 mg/d) throughout pregnancy. Average maternal weight gain in pregnancy was comparable across the three major medication categories (fluoxetine, paroxetine, sertraline).

CONCLUSION: After prenatal use of selective serotonin reuptake inhibitor antidepressant medications, neonatal complications and congenital anomalies appear to occur within general population rates. However, maternal use of high doses of fluoxetine throughout pregnancy may be associated with a risk for low birth weight.

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Argument (English):

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Keywords :

➡ depression, anxiety ; premature baby ; psychology ; low birth weight

Author of this record :

Cécile Loup — 24 May 2005

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This database is managed by Alliance francophone pour l'accouchement respecté (AFAR, https://afar.info)
affiliated with Collectif interassociatif autour de la naissance (CIANE, https://ciane.net).
It is fed by the voluntary contributions of persons interested in the sharing of scientific data.
If you agree with this project, you can support us in several ways:
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