Choose your font:
 Mukta Malar
 Open Sans Condensed
 Source Sans Pro


[Valid RSS] RSS

Database - Alliance francophone pour l'accouchement respecté (AFAR)

Description of this bibliographical database (AFAR website)
Currently 3059 records
YouTube channel (tutorial)

Created on : 24 Oct 2005
Modified on : 02 Dec 2007

 Modify this record
Do not follow this link unless you know an editor’s password!

Share: Facebook logo   Tweeter logo   Hard

Bibliographical entry (without author) :

Randomized, double-blind, placebo-controlled trial of vaginal misoprostol for management of early pregnancy failures. {USA}. Am J Obstet Gynecol. 2005 Oct;193(4):1338-43.

Author(s) :

Lister MS, Shaffer LE, Bell JG, Lutter KQ, Moorma KH.

Year of publication :


URL(s) :…

Résumé (français)  :

Abstract (English)  :

OBJECTIVE: To determine whether misoprostol medical management of early pregnancy failures is more effective than expectant management.

STUDY DESIGN: Patients diagnosed with early pregnancy failures, closed cervix, and minimal vaginal bleeding were randomized to 800 microg of misoprostol or placebo placed vaginally. Patients were evaluated by ultrasound imaging 24 hours and 48 hours after study drug administration, with repeat administration if 24-hour imaging showed a persistent gestational sac. Treatment success was defined as expulsion of uterine contents within 48 hours. Patient follow-up occurred 2 weeks after expulsion of uterine contents.

RESULTS: Treatment success occurred in 15 of 18 (83%) misoprostol patients and 2 of 16 (13%) placebo patients (P < .0001). Side effects were similar between groups except for vaginal bleeding, which was more common in the misoprostol group (P = .001). Patient satisfaction and pain perception were similar between groups.

CONCLUSION: Misoprostol appears to be highly effective for treating early pregnancy failures, with few side effects and high patient satisfaction.

Sumário (português)  :

Comments :

Argument (français) :

Le misoprostol à dose massive très efficace pour achever les fausses-couches à la grande satisfaction des patientes …

Argument (English):

Argumento (português):

Keywords :

➡ duration of labour ; active management of labor ; stillbirth ; misoprostol (Cytotec) ; induction of labor

Author of this record :

Cécile Loup — 24 Oct 2005
➡ latest update : Bernard Bel — 02 Dec 2007

Discussion (display only in English)
➡ Only identified users

 I have read the guidelines of discussions and I accept all terms (read guidelines)


New expert query --- New simple query

Creating new record --- Importing records

User management --- Dump database --- Contact


This database is managed by Alliance francophone pour l'accouchement respecté (AFAR,
affiliated with Collectif interassociatif autour de la naissance (CIANE,
It is fed by the voluntary contributions of persons interested in the sharing of scientific data.
If you agree with this project, you can support us in several ways:
(1) contributing to this database if you have a minimum training in documentation
(2) or financially supporting AFAR (see below)
(3) or joining the AFAR (or another society affiliated with CIANE).
Sign in or create an account to follow changes or become an editor.
Contact afar.association(arobase) for more information.

Valid CSS! Valid HTML!
Donating to AFAR (click “Faire un don”) will help us to maintain and develop sites and public
databases towards the support of parents and caregivers’ informed decisions with respect to childbirth