Choose your font:
 Arimo
 Merriweather
 Mukta Malar
 Open Sans Condensed
 Rokkitt
 Source Sans Pro
 Login


 English 
 Français 
 Português 
 Español 

[Valid RSS] RSS
bar

Database - (CIANE)

Description of this bibliographical database (CIANE website)
Currently 3108 records
YouTube channel (tutorial)

https://ciane.net/id=1895

Created on : 28 Mar 2006
Modified on : 02 Dec 2007

 Modify this record
Do not follow this link unless you know an editor’s password!


Share: Facebook logo   Tweeter logo   Hard

Bibliographical entry (without author) :

Induction of labor with misoprostol in pregnancies with advanced maternal age. {Turquie}. Eur J Obstet Gynecol Reprod Biol. 2006 Jan 4;

Author(s) :

Zeteroglu S, Sahin GH, Sahin HA.

Year of publication :

2006

URL(s) :

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=…

Résumé (français)  :

Abstract (English)  :

OBJECTIVE: The objective was to compare the efficacy and complications of intravaginal misoprostol application with oxytocin infusion for induction of labor in advanced aged pregnancies with a Bishop score of <6.

STUDY DESIGN: A hundred advanced aged (>=35 years) pregnant patients with a Bishop score of <6 were randomized into two groups. The first group (50 patients) received 50mug intravaginal misoprostol four times with 4h intervals and the second group received oxytocin infusion for induction of labor starting from 2mIU/min and was increased every 30min with 2mIU/min increments up to a maximum of 40mIU/min. The time from induction to delivery, the route of delivery, fetal outcome, and maternal complications were recorded. Statistical analyses were performed using the Mann-Whitney U, Chi-squared and t tests to determine differences between the two groups. A p value <=0.05 was considered significant.

RESULTS: Misoprostol was superior for induction of labor in advanced aged pregnancies with Bishop score of <6, as the mean time from induction to delivery was 9.61+/-4.12h and 11.46+/-4.86h in the misoprostol and oxytocin groups respectively, with a significant difference between the groups (p=0.04). The rate of vaginal delivery was higher in the misoprostol group (84.0%) than in the oxytocin group (80.0%), but the difference did not reach significance (p=0.60). The rates of placental abruption and postpartum hemorrhage were similar in both groups and no cases of uterine rupture occurred. The 1- and 5-min mean Apgar scores were 6.98+/-1.17 to 9.08+/-0.99 and 6.88+/-1.81 to 9.00+/-1.35 in the misoprostol and oxytocin groups respectively, with no significant differences between the groups (p=0.74, p=0.83). No cases of asphyxia were present. The rate of admission to the neonatal intensive care unit was similar in both groups.

CONCLUSION: Intravaginal misoprostol seems to be an alternative method to oxytocin in the induction of labor in advanced aged pregnant women with low Bishop scores, as it is efficacious, cheap, and easy to use. But large studies are necessary to clarify safety with regard to the rare complications such as uterine rupture.

Sumário (português)  :

Resumen (español)  :

Comments :

Argument (français) :

Argument (English):

Argumento (português):

Argumento (español):

Keywords :

➡ c-section/caesarean ; evidence-based medicine/midwifery ; maternal age ; postpartum hemorrhage ; induction of labor ; misoprostol (Cytotec) ; oxytocin ; post-term pregnancy

Author of this record :

Cécile Loup — 28 Mar 2006

Discussion (display only in English)
 
➡ Only identified users



 I have read the guidelines of discussions and I accept all terms (read guidelines)

barre

New expert query --- New simple query

Creating new record --- Importing records

User management --- Dump database --- Contact

bar

This database created by Alliance francophone pour l'accouchement respecté (AFAR) is managed
by Collectif interassociatif autour de la naissance (CIANE, https://ciane.net).
It is fed by the voluntary contributions of persons interested in the sharing of scientific data.
If you agree with this project, you can support us in several ways:
(1) contributing to this database if you have a minimum training in documentation
(2) or financially supporting CIANE (see below)
(3) or joining any society affiliated with CIANE.
Sign in or create an account to follow changes or become an editor.
Contact bibli(arobase)ciane.net for more information.

Valid CSS! Valid HTML!
Donating to CIANE (click “Faire un don”) will help us to maintain and develop sites and public
databases towards the support of parents and caregivers’ informed decisions with respect to childbirth