Choose your font:
 Mukta Malar
 Open Sans Condensed
 Source Sans Pro


[Valid RSS] RSS

Database - Alliance francophone pour l'accouchement respecté (AFAR)

Description of this bibliographical database (AFAR website)
Currently 3059 records
YouTube channel (tutorial)

Created on : 24 Dec 2008
Modified on : 29 Oct 2018

 Modify this record
Do not follow this link unless you know an editor’s password!

Share: Facebook logo   Tweeter logo   Hard

Bibliographical entry (without author) :

Cell-free fetal DNA in maternal circulation after amniocentesis. Clin Chem 49:1193–1195.

Author(s) :

Samura O, et al.

Year of publication :


URL(s) :

Résumé (français)  :

Abstract (English)  :

After amniocentesis, 5–20% of patients have evidence of fetal-maternal hemorrhage as indicated by increases in maternal serum α-fetoprotein (1)(2)(3)(4)(5) or by the Betke–Kleihauer test (6)(7)(8). The Betke–Kleihauer test can differentiate fetal from maternal erythrocytes by the relative resistance of hemoglobin F-containing cells to acid elution, and it is the most popular method of diagnosing and assessing the severity of fetal-maternal hemorrhage (9). The reliability of this test has been questioned, however, because numerous sources of error are associated with it (10). These sources of error possibly contribute to the wide variation in the reported incidence of fetal-maternal hemorrhage; a more accurate method of assessing fetal-maternal hemorrhage is therefore required in the clinical setting of rhesus D-negative pregnant women.

Sumário (português)  :

Full text (public) :

Comments :

Argument (français) :

L’amniocentèse perturbe considérablement l’interface mère-placenta; des études complémentaires sont nécessaires pour déterminer si l’ADN fœtal est un marqueur sensible des hémorragies materno-fœtales ou si son augmentation après l’amniocentèse reflète le transfert de l’ADN du liquide amniotique à la circulation maternelle.

Argument (English):

Amniocentesis significantly disturbs the maternal-placental interface; further studies are needed to determine whether fetal DNA is a sensitive marker for fetal-maternal hemorrhage or whether its increase after amniocentesis reflects transfer of DNA from amniotic fluid to the maternal circulation.

Argumento (português):

A amniocentese perturba significativamente a interface materno-placentária; mais estudos são necessários para determinar se o DNA fetal é um marcador sensível de hemorragia fetal-materna ou se seu aumento após a amniocentese reflete a transferência de DNA do líquido amniótico para a circulação materna.

Keywords :

➡ antenatal diagnosis

Author of this record :

Bernard Bel — 24 Dec 2008
➡ latest update : Bernard Bel — 29 Oct 2018

Discussion (display only in English)
➡ Only identified users

 I have read the guidelines of discussions and I accept all terms
[Hide guidelines]

➡ Discussion guidelines

1) Comments aim at clarifying the content of the publication or suggesting links for a better comprehension of its topic
2) All comments are public and opinions expressed belong to their authors
3) Avoid casual talk and personal stories
4) Any off-topic comment or containing inappropriate statements will be deleted without notice


New expert query --- New simple query

Creating new record --- Importing records

User management --- Dump database --- Contact


This database is managed by Alliance francophone pour l'accouchement respecté (AFAR,
affiliated with Collectif interassociatif autour de la naissance (CIANE,
It is fed by the voluntary contributions of persons interested in the sharing of scientific data.
If you agree with this project, you can support us in several ways:
(1) contributing to this database if you have a minimum training in documentation
(2) or financially supporting AFAR (see below)
(3) or joining the AFAR (or another society affiliated with CIANE).
Sign in or create an account to follow changes or become an editor.
Contact afar.association(arobase) for more information.

Valid CSS! Valid HTML!
Donating to AFAR (click “Faire un don”) will help us to maintain and develop sites and public
databases towards the support of parents and caregivers’ informed decisions with respect to childbirth