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Database - Alliance francophone pour l'accouchement respecté (AFAR)

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Currently 3059 records
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Created on : 26 Nov 2017
Modified on : 26 Nov 2017

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Bibliographical entry (without author) :

Meta-analysis of Foley catheter plus misoprostol versus misoprostol alone for cervical ripening - International Journal of Gynecology and Obstetrics - Vol. 129, 3 - p.193-198

Author(s) :

Chen, W.; Xue, J.; Gaudet, L.; Walker, M.; Wen, S.W.

Year of publication :


URL(s) :…

Résumé (français)  :

Abstract (English)  :

Background The effectiveness of Foley catheter plus misoprostol for cervical ripening has not been convincingly shown in trials. Objectives To summarize the evidence comparing Foley catheter plus misoprostol versus misoprostol alone for cervical ripening. Search strategy Embase, Medline, and Cochrane Collaboration databases were searched with the terms “Foley catheter,“ “misoprostol,“ “cervical ripening,“ and “labor induction.“ Selection criteria Randomized controlled trials comparing the methods of cervical ripening for delivery of a viable fetus were included. Data collection and analysis Study characteristics, quality, and outcomes were recorded. Random-effects models were used to combine data. Main results Eight trials were included, with 1153 patients overall. In a pooled analysis of seven high-quality studies, the combination group had a decreased time to delivery (mean difference -2.36 hours, 95% confidence interval [CI] -4.07 to -0.66; P = 0.007). Risk of chorioamnionitis was significantly increased in the combination group (risk ratio [RR] 2.07, 95% CI 1.04-4.13; P = 0.04), and that of tachysystole with fetal heart rate changes was decreased (RR 0.58, 95% CI 0.38-0.91; P = 0.02). Frequency of cesarean did not differ (P = 0.77). Conclusions The combined use of Foley catheter and misoprostol results in a reduced time to delivery, a reduced frequency tachysystole with fetal heart rate changes, and an increased incidence of chorioamnionitis. © 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

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Keywords :

➡ induction of labor ; ripening of cervix ; misoprostol (Cytotec)

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Import 26/11/2017 — 26 Nov 2017
➡ latest update : Bernard Bel — 26 Nov 2017

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This database is managed by Alliance francophone pour l'accouchement respecté (AFAR,
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