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Database - Alliance francophone pour l'accouchement respecté (AFAR)

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Created on : 26 Nov 2017
Modified on : 26 Nov 2017

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Bibliographical entry (without author) :

Vaginal misoprostol and cervical ripening balloon for induction of labor in late-term pregnancies - Journal of Obstetrics and Gynaecology Research - Vol. 43, 1 - p.87-91

Author(s) :

Duro Gómez, J.; Garrido Oyarzún, M.F.; Rodríguez Marín, A.B.; de la Torre González, A.J.; Arjona Berral, J.E.; Castelo-Branco, C.

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Abstract (English)  :

Aim: The aim of this study was to compare vaginal misoprostol with the Cook cervical ripening balloon (CCRB) for induction of labor in late-term nulliparous women. Methods: This open, quasi-experimental, prospective study included 109 nulliparous women with late-term pregnancies and Bishop scores < 7. Fifty-five women were allocated to receive vaginal misoprostol 25 mcg and 54 received the CCRB to induce labor. The primary outcome was the time until delivery. Secondary outcomes included time to the onset of labor and obstetric and perinatal outcomes. Results: Women in the misoprostol group experienced shorter time until delivery (25.41 h vs 31.26 h; P < 0.01) and in a greater percentage gave birth within the first 24 h. Time to active stage of labor was 19.5 h and 23.8 h (P < 0.01) for misoprostol and the CCRB, respectively. There were no differences in the rates of cesarean section or post-partum anemia. Additionally, there were no differences in rates of tachysystolia, intrapartum fever, or meconium. Perinatal outcomes, post-partum pH, Apgar scores, and neonatal admissions were similar in the two groups. Conclusion: Misoprostol 25 mcg reduces labor induction time compared with the CCRB with similar safety in late-term pregnancies. © 2016 Japan Society of Obstetrics and Gynecology

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Keywords :

➡ induction of labor ; ripening of cervix ; misoprostol (Cytotec)

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Import 26/11/2017 — 26 Nov 2017
➡ latest update : Bernard Bel — 26 Nov 2017

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