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Database - Alliance francophone pour l'accouchement respecté (AFAR)

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Created on : 26 Nov 2017
Modified on : 26 Nov 2017

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Bibliographical entry (without author) :

Sequential Versus Concurrent Use of Vaginal Misoprostol Plus Foley Catheter for Induction of Labor: A Randomized Clinical Trial - - p.1

Author(s) :

El Sharkwy, I.A.E.; Noureldin, E.H.; Mohamed, E.A.E.; Shazly, S.A.

Year of publication :


URL(s) :…

Résumé (français)  :

Abstract (English)  :

Background: To compare between the sequential and concurrent use of vaginal misoprostol plus Foley catheter for labor induction. Methods: This single-center, non-blinded randomized study was conducted at the department of Obstetrics and Gynecology, Faculty of medicine, Zagazig University. A total of 160 women with full term singleton pregnancy, cephalic presentation and bishop score ≤ 6 were randomized for labor induction with either concurrent or sequential use of vaginal misoprostol plus Foley catheter (80 cases in each group). The primary outcome measured was induction-to-delivery interval and secondary outcomes mesaured were vaginal delivery within 24 h, number of doses needed to induce labor, need of oxytocin for augmentation of labor, cesarean section rate, maternal or neonatal complications. Results: The mean induction-to-delivery interval was 22.33 ± 13.28 h versus 18.45 ± 14.34 h (p = 0.041) in sequential and concurrent group, respectively. The percentage of women who completed vaginal delivery within 24 h was 51% versus 61% (p = 0.046) in sequential and concurrent group, respectively. Other maternal and neonatal outcomes were similar in both groups Conclusion: Concurrent use of vaginal misoprostol plus Foley catheter for labor induction was associated with shorter induction-to delivery interval compared to sequential use, and it increases the rate of vaginal delivery in the first 24 h. © 2017 Federation of Obstetric & Gynecological Societies of India

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Keywords :

➡ induction of labor ; misoprostol (Cytotec)

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Import 26/11/2017 — 26 Nov 2017

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