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Database - Alliance francophone pour l'accouchement respecté (AFAR)

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Created on : 26 Nov 2017
Modified on : 26 Nov 2017

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Bibliographical entry (without author) :

Comparative study of efficacy of misoprostol vs dinoprostone gel for induction of labour - JK Science - Vol. 18, 3 - p.166-171

Author(s) :

Gupta, S.; Hak, J.; Kumar, D.

Year of publication :


URL(s) :…

Résumé (français)  :

Abstract (English)  :

A cross-sectional study has been undertaken to compare the safety and efficacy of intra-vaginal misoprostol (PGE1 analogue) with intra-cervical dinoprostone (PGE2) in progress and induction of labour, the maternal side effects and the foetal outcome. The study included 100 patients requiring induction of labour, admitted in antenatal ward, Department of Obstetrics and Gynaecology, SMGS Hospital, Government Medical College, Jammu. Group I comprised of 50 patients who underwent induction with misoprostol vaginal tablets and Group II comprised of 50 patients who underwent induction with dinoprostone intra cervical gel. Labour induction was considered successful if subjects delivered within 24 hours of initiation of either of two methods. Data between misoprostol group and dinoprostone gel group was analyzed by using unpaired t test to find out the differences between the two means and by Chi-square t test where data was in number and percentages. The two tailed probability value (p < 0.05) was considered as statistically significant. The maternal and foetal outcome were measured i.e., Bishop’s score, time intervals from induction to delivery, need for oxytocin, mode of delivery, maternal and foetal side effects. The results of the present study show that the time intervals from induction-delivery intervals were significantly shorter and the requirement of oxytocin was less for augmentation of the labour in the misoprostol group than dinoprostone gel group. Conclusion: Intravaginal misoprostol is an effective agent for induction of labour than intra cervical gel. The drug is easy to use, effective and safe to mother and the foetus. Misoprostol is cheaper and is stable at. © 2017, JK Science. All rights reserved.

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Keywords :

➡ induction of labor ; misoprostol (Cytotec)

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Import 26/11/2017 — 26 Nov 2017

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