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Database - Alliance francophone pour l'accouchement respecté (AFAR)

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Created on : 26 Nov 2017
Modified on : 26 Nov 2017

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Bibliographical entry (without author) :

The effectiveness of misoprostol or dinoprostone in neonatal outcome after labour induction in post-term nulliparas - Clinical and Experimental Obstetrics and Gynecology - Vol. 42, 5 - p.649-652

Author(s) :

Soilemetzidis, M.; Pinidis, P.; Tsagias, N.; Ammari, A.; Liberis, A.; Liberis, V.; Galazios, G.; Tsikouras, P.

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Abstract (English)  :

Objective: The object of this study was to investigate the efficacy of vaginal administration of misoprostol versus dinoprostone in neonatal outcome. Materials and Methods: The first Group A included 77 pregnant women, who requested pregnancy termination one week after labour term and received vaginally misoprostol 50 μg, while the other 69 pregnant women in Group B were vaginally administrated three mg dinoprostone. According to the authors’ protocol this procedure was repeated after six hours for a maximum of two times. Results: The labour duration was longer in Group B (p = 0.000), while the APGAR score was better in Group A(p = 0.015). In Group A the labour modus was as follows: 86.9% normal vaginal labour, 3.8% vacuum extraction, and 9.3% cesarean section, while in Group B it was 82.83% normal vaginal labour, 3.07% vacuum extraction, and 14.1% cesarean section. Conclusion: Misoprostol has advantages according to neonatal outcome compared to administration of dinoprostone.

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Keywords :

➡ induction of labor ; misoprostol (Cytotec)

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Import 26/11/2017 — 26 Nov 2017

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