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Created on : 26 Nov 2017
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Bibliographical entry (without author) :

A randomised comparison of patient satisfaction with vaginal and sublingual misoprostol for induction of labour at term - BJOG: An International Journal of Obstetrics and Gynaecology - Vol. 114, 10 - p.1215-1221

Author(s) :

Nassar, A.H.; Awwad, J.; Khalil, A.M.; Abu-Musa, A.; Mehio, G.; Usta, I.M.

Year of publication :


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Résumé (français)  :

Abstract (English)  :

Objective: To compare patient satisfaction with two routes of misoprostol for term labour induction. Design: Prospective randomised trial. Setting: Tertiary care hospital. Population: A total of 170 women admitted at ≥37 weeks of gestation for induction of labour. Methods: Women were randomised to receive 50 micrograms of either sublingual or vaginal misoprostol. Main outcome measures: Patient satisfaction with the route of administration. Results: Despite a similar proportion reporting the labour induction as more painful than expected in both groups, a significantly lower proportion mentioned that the pelvic examinations were very painful in the sublingual group (19.7 versus 36.1%, relative risk [RR] 0.5, 95% CI 0.3-0.9). Request for analgesia was similar in both groups. More women in the sublingual group thought that the labour experience was better than expected (RR 2.0, 95% CI 1.2-3.3), had a positive attitude towards induction in subsequent pregnancies (RR 1.6, 95% CI 1.1-2.3) and preferred the same route in subsequent pregnancies (RR 3.1, 95% CI 2.2-4.5). Mean number of misoprostol doses, oxytocin augmentation, tachysystole and hyperstimulation, induction to vaginal delivery interval, vaginal delivery after a single dose, vaginal birth within 12 and 24 hours, and caesarean delivery rates were similar in both groups. Conclusion: Sublingual misoprostol (50 micrograms) is associated with a significantly higher patient satisfaction rate compared with a similar dose of vaginal misoprostol. Sublingual administration offers additional choice to women, in particular those wishing to avoid vaginal administration. © RCOG 2007 BJOG An International Journal of Obstetrics and Gynaecology.

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Keywords :

➡ induction of labor ; misoprostol (Cytotec)

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Import 26/11/2017 — 26 Nov 2017

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