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Database - Alliance francophone pour l'accouchement respecté (AFAR)

Description of this bibliographical database (AFAR website)
Currently 3059 records
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Created on : 28 May 2004
Modified on : 02 Dec 2007

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Bibliographical entry (without author) :

Risk of uterine rupture in labor induction of patients with prior cesarean section: an inner city hospital experience. {USA}. American Journal of Obstetrics and Gynecology 2004;190(5):1476-1478.

Author(s) :

Lin C, Raynor BD.

Year of publication :


URL(s) :…

Résumé (français)  :

Abstract (English)  :

OBJECTIVE: This study was undertaken to determine the risk of uterine rupture in patients induced with oxytocin or misoprostol after 1 or more previous cesarean sections.

STUDY DESIGN: Patients with 1 or more previous cesarean sections who delivered after 28 weeks’ gestation between 1996 and 2002 were identified by database. Among 3533 total patients, rates of uterine rupture were compared among 4 groups: oxytocin induction (n = 430), misoprostol induction (n = 142), spontaneous labor (n = 2523), and repeat cesarean section without labor (n = 438). Statistical analysis included chi(2) test, Fisher exact test, unpaired t test, and Mantel-Haenszel test.

RESULTS: Rate of rupture was increased in all inductions compared with that of the spontaneous labor group. Among patients with 1 prior cesarean, rupture rates with misoprostol and oxytocin induction were 0.8% and 1.1%, respectively.

CONCLUSION: Induction of labor with oxytocin or misoprostol is associated with a higher rate of uterine rupture compared with those who deliver after spontaneous labor. After 1 prior cesarean, rupture rate with misoprostol induction is not increased compared with oxytocin induction.

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Argument (English):

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Keywords :

➡ vaginal birth after caesarean ; c-section/caesarean ; evidence-based medicine/midwifery ; induction of labor ; misoprostol (Cytotec) ; oxytocin ; post-term pregnancy

Author of this record :

Cécile Loup — 28 May 2004

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