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Database - Alliance francophone pour l'accouchement respecté (AFAR)

Description of this bibliographical database (AFAR website)
Currently 3059 records
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Created on : 26 Oct 2005
Modified on : 25 Jun 2018

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Bibliographical entry (without author) :

Misoprostol vs. oxytocin for induction of labor. {Soudan}. Int J Gynaecol Obstet. 2005 Sep 12 (preprint).

Author(s) :

Elhassan EM, Mirghani OA, Adam I.

Year of publication :


URL(s) :…

Résumé (français)  :

Abstract (English)  :

An open randomized controlled clinical trial was conducted at the labor ward of Wad Medani Hospital, Sudan to test the efficacy of misoprostol vs. oxytocin for labor induction. Patients admitted from August 2004 through February 2005 were approached for participation in the study. Inclusion criteria were specific women with single live babies, with a favorable cervix (Bishop Score > 5) and intact membranes.
Women were assigned to receive either vaginal misoprostol 50 μ (Cytotec, Searle), six hourly until initiation of labor or maximum of 4 doses or an intravenous infusion of 2 mU/min, which was doubled at 30-min intervals until the appropriate contraction pattern was obtained or dose was increased to a maximum of 20 mU/min and maintained as such.
Induction–delivery interval was significantly shorter in misoprostol group (8.2 ± 1.1 vs. 12.04 ± 1.5 h) vs. oxytocin group. The rate of vaginal delivery was significantly high in misoprostol group, and cesarean section rate was significantly low in misoprostol group.

Sumário (português)  :

Comments :

Argument (français) :

Efficacité du misoprostol par rapport a l’ocytocine pour le déclenchement: 8h en moyenne au lieu de 12h pour une voie basse, et moins de césariennes

Argument (English):

Efficacy of misoprostol compared to oxytocin for onset: 8h on average instead of 12h for a low pathway, and fewer caesareans

Argumento (português):

Eficácia do misoprostol em comparação com a ocitocina para o início: 8h em média, em vez de 12h para uma via baixa, e menos cesarianas

Keywords :

➡ c-section/caesarean ; evidence-based medicine/midwifery ; induction of labor ; post-term pregnancy ; misoprostol (Cytotec) ; oxytocin

Author of this record :

Cécile Loup — 26 Oct 2005
➡ latest update : Bernard Bel — 25 Jun 2018

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